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Table 4 Sequences of dry-cured ham-derived dipeptides presenting both bioactivity and sensory characteristics according to the BIOPEP database (access May 2019)

From: The relevance of dipeptides and tripeptides in the bioactivity and taste of dry-cured ham

Peptide sequencea

Mass (Da)b

Proteins of originc

Bioactivity

Sensory

ACE inhibitor

Renin inhibitor

DPP IV inhibitor

Glucose uptake stimulating

Antioxidant activity

DPP III inhibitor

Bitter

Umami

Sour

Sweet

Umami enhancing

Salty enhancing

AA

160.17

MLC

x

 

x

      

x

  

AD

204.18

MLC, MHC

  

x

   

x

x

    

EA

218.21

TTN, MYG

x

     

x

x

    

EF

278.35

UBQ

 

x

    

x

     

EI

260.29

TTN, TROP T

x

 

x

   

x

     

EK

275.30

MLC

x

 

x

    

x

    

EL

244.33

ENO

    

x

 

x

     

GP

172.18

TTN

x

 

x

   

x

     

II

244.33

ENO

  

x

x

  

x

     

IL

244.33

ENO

x

 

x

x

  

x

     

KP

243.30

TTN

x

 

x

 

x

 

x

     

LA

202.25

CK

x

 

x

  

x

x

     

LG

188.23

MLC

x

     

x

     

LL

244.33

LDH

  

x

x

  

x

     

PA

186.21

MLC, TTN, LDB3

  

x

   

x

     

PE

244.25

MLC, TTN

     

x

    

x

 

PK

243.30

TTN

  

x

   

x

     

PL

228.29

CK

x

 

x

   

x

     

PP

212.25

TTN

x

 

x

   

x

     

RG

231.25

ENO

x

 

x

   

x

    

x

VE

246.26

TTN, CK

x

 

x

   

x

x

x

   

VF

264.32

MLC, CK

x

 

x

   

x

     

VV

216.28

LDB3

  

x

   

x

x

    

VY

280.32

ENO

x

 

x

 

x

x

x

     
  1. aPeptide sequences are given as amino acids one-letter code
  2. bMass of the peptide sequence in Daltons calculated using PeptideMass from ExPASy
  3. cPossible proteins of origin of the peptides. Names of the abbreviated proteins are given in Table 1