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Fig. 4 | Food Production, Processing and Nutrition

Fig. 4

From: Muscadine or amla extracts standardized to ellagic acid content ameliorate glucolipotoxicity associated β-cell dysfunction via inhibition of IL-1β and improved insulin secretion

Fig. 4

a Effect of ellagic acid (EA), muscadine (MS), amla (AM), or urolithin A (UR) at 0.01-10 μM concentrations on 33.3 mM glucose (Glu)-reduced insulin levels in NIT-1 cells. b Effect of ellagic acid (EA), muscadine (MS), amla (AM), or urolithin A (UR) at 0.01-10 μM concentrations on 250 μM palmitic acid (PA)-reduced insulin levels in NIT-1 cells. c Effect of ellagic acid (EA), muscadine (MS), amla (AM), or urolithin A (UR) at 0.01-10 μM concentrations on 33.3 mM glucose (Glu) + 250 μM palmitic acid (PA)-reduced insulin levels in NIT-1 cells. The values are expressed as percentage of untreated control. Results are presented as mean ± S.D., (n = 2). Letters with different superscripts are significantly different (P < 0.05) among groups

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