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Table 2 Other bioactivities attributed to the dipeptides of this study

From: Inhibition of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase enzyme by dipeptides identified in dry-cured ham

Dipeptidea Bioactivity Biological system Reference
AA in vitro ACEI inhibitor cardiovascular Gallego et al., 2014
in vitro DPP-IV inhibitor endocrine Sentandreu & Toldrá, 2007
AL in vitro DPP-IV inhibitor endocrine Nongonierma et al., 2014
inhibition of NO production in RAW 264.7 immune Zhao et al., 2016
AQ intestinal permeability reduction and wound-healing properties digestive Zhou et al., 2004
inhibition of pro-inflammatory cytokines by polymorphonuclear leukocytes immune Fürst et al., 2004
AW in vitro antioxidant cardiovascular Liu et al., 2015
in vitro ACEI inhibitor endocrine Loponen, 2008
in vitro DPP-IV inhibitor Nongonierma et al., 2014
Udenigwe, Li, & Aluko, 2012
in silico renin inhibitor
DA in vitro ACEI inhibitor cardiovascular Cushman et al., 1981
in vitro DPP-III inhibitor endocrine Dhanda et al., 2007
DD (absent)   
DG in vitro ACEI inhibitor cardiovascular Meisel et al., 2006
EE stimulating vasoactive substance release cardiovascular Ringseis et al., 2005
ES in vitro DPP-IV inhibitor endocrine Lan et al., 2015
EV in vitro ACEI inhibitor cardiovascular van Platerink et al., 2008
in vitro DPP-IV inhibitor endocrine Lan et al., 2015
GA ACEI inhibitor cardiovascular Cheung et al., 1980
in vitro DPP-IV inhibitor endocrine Hikida et al., 2013
LE (absent)   
LL in vitro DPP-IV inhibitor endocrine Bella et al., 1982
glucose uptake stimulating compound immune Morifuji et al., 2009
in silico anti-inflammatory compound Gupta et al., 2017
PA in vitro DPP-IV inhibitor endocrine Bella et al., 1982
QQ in vitro DPP-IV inhibitor endocrine Lan et al., 2015
inhibition of pro-inflammatory cytokines by polymorphonuclear leukocytes immune Fürst et al., 2004
VG in vitro ACEI inhibitor cardiovascular Cheung et al., 1980
in vitro DPP-IV inhibitor endocrine Lan et al., 2015
VH in vitro DPP-IV inhibitor endocrine Lan et al., 2015
inhibition of NO production in RAW 264.7 immune Zhao et al., 2016
  1. aPeptide sequences are given as amino acids one-letter code