The optimization of ultrasonic-microwave assisted synergistic extraction of Lotus plumule extract rich in flavonoids and its hypoglycemic activity

Table 2 Analysis of variance of response surface quadratic model

Source	Sum of squares	df	Mean squares	F-Value	p-value Prob > F
Model	1.080943	9	0.1201048	343.8583	< 0.0001
A-Microwave power	0.0000125	1	0.0000125	0.035787	0.8553
B-Ultrasonic power	0.037813	1	0.0378125	108.2566	< 0.0001
C-Extraction time	0.01805	1	0.01805	51.67689	0.0002
AB	0.01	1	0.01	28.62986	0.0011
AC	0.005625	1	0.005625	16.10429	0.0051
BC	0.001225	1	0.001225	3.507157	0.1033
A²	0.071706	1	0.0717063	205.2942	< 0.0001
B²	0.432506	1	0.4325063	1238.259	< 0.0001
C²	0.412501	1	0.4125011	1180.985	< 0.0001
Residual	0.002445	7	0.0003493
Lack of fit	0.001525	3	0.0005083	2.210145	0.2294
Pure error	0.00092	4	0.00023
Cor total	1.083388	16
R²	0.9977

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