Fig. 5
From: Crocodile blood supplementation protects vascular function in diabetic mice
Ex vivo CBSF co-incubation remedied IL-1β-impaired EDR in C57BL/6 J mouse aortae. Effect of IL-1β (1 pg/mL) incubation on EDR of isolated aortae from C57BL/6 J mice (a). Effect of CBSF co-incubation on EDR of IL-1β-treated aortae from C57BL/6 J mice (b). Effect of IL-1β incubation on endothelium-independent relaxation of isolated aortae from C57BL/6 J mice (c). Effect of CBSF co-incubation on endothelium-independent relaxation of IL-1β-treated aortae from C57BL/6 J mice (d). Data are presented in means ± SEM; n = 5; *p < 0.05, **p < 0.01 compared to IL-1β-treated group. CBSF, crocodile blood soluble fraction; Phe, phenylephrine; ACh, acetylcholine; SNP, sodium nitroprusside