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Table 1 Histopathological scoring system to quantify the degree of intestinal lesions

From: Immobilization of Lactobacillus plantarum NCIMB 8826 ameliorates Citrobacter rodentium induced lesions and enhances the gut inflammatory response in C57BL/6 weanling mice

Criterion

Score

0

1

2

3

Mucosal Hyperplasia

–

↑

↑↑

↑↑↑

Mucosal Inflammation

–

↑

↑↑

↑↑↑

Submucosal Inflammation

–

–

↑

↑↑

Goblet Cell Number

–

↓

↓↓

↓↓↓

Erosion/Ulceration

–

↑

↑↑

↑↑↑

  1. The scoring system adapted from Van der Sluis et al. (2006) was also used by Wine et al. (2010)
  2. ↑Indicates an increase in the degree of intestinal lesions levels
  3. ↓Indicates a decrease in the degree of intestinal lesions levels
  4. —Indicates that the scoring system did not quantify the degree of intestinal lesions. The number of arrows reflects the degree of the lesion