Bitter gourd flavored Non-Alcoholic Wheat Beer (NAWB) exhibited antidiabetic properties by modulating carbohydrate metabolizing enzymes and upregulates insulin and GLUT-2 mRNA expressions in High Fat Diet/Streptozotocin (HFD/STZ) induced diabetic rats

Table 3 Fasting blood sugar, Fasting Insulin and HOMA-IR levels of STZ-induced diabetic rats treated with bitter gourd flavored Non-alcoholic Wheat Beer

Group	FBS (mg/dL)	FI (µU/ml)	HOMA-IR
NC	81.00 ± 7.62	11.85 ± 1.74	2.37 ± 0.07
DC	372.74 ± 11.53	9.31 ± 0.98	8.55 ± 1.60
Acarbose	103.50 ± 0.71	8.62 ± 0.44	2.20 ± 0.10
HP	102.67 ± 8.74	10.62 ± 0.87	2.69 ± 0.31
BG	87.33 ± 7.77	9.15 ± 0.65	1.97 ± 0.25
75:25BG	103.67 ± 9.19	9.85 ± 1.52	2.52 ± 0.17
50:50BG	93.00 ± 2.89	9.62 ± 0.76	2.21 ± 0.21
25:75BG	81.67 ± 2.89	10.89 ± 1.96	2.20 ± 0.24

Results are expressed as mean ± standard deviations (n = 5)
HP (STZ + 100%Hops); BG (STZ + 100% Bitter gourd); 75:25BG (STZ + 75%Hops25%Bitter Gourd); 50:50BG (STZ + 50%Hops50%Bitter Gourd); 25:75BG (STZ + 25%Hops75%Bitter Gourd); Acarbose (STZ + Acarbose); DC (STZ-diabetic control group); NC (Normal Control group)
FBS Fasting Blood Sugar, FI Fasting Insulin, HOMA-IR Homeostatic Model Assessment for Insulin Resistance

ISSN: 2661-8974