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Table 2 Summary of detected compounds in Tapuy wine and lees using LC–MS/MS

From: Phenolic-rich lees from Philippine rice wine (tapuy) increases Caenorhabditis elegans lifespan in spite of having low antioxidant activity

 

Tapuy Wine

Tapuy Lees

Known Functions

Compound Class

Reference(s)

( +)-bakuchiol

 

Anti-aging

Antioxidative properties

Protective effects against diabetic cardiomyopathy

Phenol

Ma et al. 2020; Bluemke et al. 2022; Chaudhuri & Bojanowski 2014; Dhaliwal et al. 2019)

25S-inokosterone

 

Enhances the lifespan of yeast models and mammalian cells

Antioxidative properties

Steroid

Liu et al. 2022)

4, 8, 12-trimethyltridecanoic acid

 

 

Fatty acid

Shahrajabian et al. 2021)

4-hydroxy ginkgolic acid

 

Antibacterial

Neuroprotective effects

Antioxidative properties

Antiaging

Antiobesity

Antidiabetic

Antidementia

Phenol

Noor-E-Tabassum et al. 2022; Mango et al. 2016; Hua et al. 2017)

6-hydroxykaempferol

 

Antioxidant

Reduces risk of chronic diseases

Anticancer effects

Neuroprotective effects

Anti-inflammatory properties

Flavonoid

Chen & Chen 2014; Ren et al. 2019; Silva dos Santos et al. 2021)

Akebonoic acid

  

Terpenoid

Maciąg et al. 2021; Huang et al. 2022)

Astramembranin II

  

Glycoside

 

Chasmanin

 

 

Alkaloid

 

Cholestenone

 

Antibacterial

Antioxidant

Antidiabetes effects

Steroid

Ramalingam & Rajaram 2018; Neuvonen et al. 2014; Kobayashi et al. 2021; Nagao et al. 2022)

ent-Kauran-16a, 17-diol

 

Protects against neuroinflammation

Terpene

Dutra et al. 2014; Nhiem et al. 2014; Kim et al. 2016)

Flazin

 

Anti-HIV

Antioxidant

Immunomodulatory activity

Lipid droplet regulator

Alkaloid

Fuda et al. 2019; Wu et al. 2022; Tang et al. 2008; Kong et al. 2021)

Ganoderic acid B

 

Antimicrobial

Antioxidant

Anti-HIV

Triterpenoid

Cör et al. 2018; Sheikha 2022; Chen 2020)

Kalmanol

 

Terpenoid

 

Kushenol E

 

Autophagy regulation

Flavonoid

Kwon et al. 2020)

Kushenol Q

 

 

Flavonoid

 

Pterodondiol

  

Terpenoid

 

Rengyoside C

 

   

Robinetin

 

 

Flavonoid

 

Silydianin

 

   

Strophanthidine

 

Anticancer

Antiviral

Glycoside

Reddy et al. 2020)

Tuberostemonone

 

 

Alkaloid

 

α-ionone

  

Terpene